Neuron Sub-Compartments Exhibit Opposite Rheological and Mechanosensitive Properties
نویسندگان
چکیده
منابع مشابه
Opposite rheological properties of neuronal microcompartments predict axonal vulnerability in brain injury
Although pathological changes in axonal morphology have emerged as important features of traumatic brain injury (TBI), the mechanical vulnerability of the axonal microcompartment relative to the cell body is not well understood. We hypothesized that soma and neurite microcompartments exhibit distinct mechanical behaviors, rendering axons more sensitive to a mechanical injury. In order to test t...
متن کاملShort and Long Term Measures of Anxiety Exhibit Opposite Results
Animal models of human diseases of the central nervous system, generalized anxiety disorder included, are essential for the study of the brain-behavior interface and obligatory for drug development; yet, these models fail to yield new insights and efficacious drugs. By increasing testing duration hundredfold and arena size tenfold, and comparing the behavior of the common animal model to that o...
متن کاملNicotine alters mucin rheological properties.
Tobacco smoke exposure, the major cause of chronic obstructive pulmonary disease (COPD), instigates a dysfunctional clearance of thick obstructive mucus. However, the mechanism underlying the formation of abnormally viscous mucus remains elusive. We investigated whether nicotine can directly alter the rheological properties of mucin by examining its physicochemical interactions with human airwa...
متن کاملRheological Properties of Ethylcellulose Latex
Because of their large specific surface area, aqueous-based pseudolatex systems of ethylcellulose can absorb large amounts of drugs. In addition, the stability of polymeric particles in biological fluids delays the release of the drug as in controlled drug delivery systems. The aim of the present study was to characterize the rheological properties of latex particles as a measure of their collo...
متن کاملRheological properties of human saliva.
From measurements with a Couette-type viscometer provided with a guard ring it was shown that at the saliva-air interface a protein layer is adsorbed. Measurements of the surface shear modulus of this layer on saliva of 7 healthy subjects were performed at a frequency of about 70 Hz and a temperature of 25 degrees C. For a surface age of about 1.5 h the surface shear modulus and the surface vis...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Biophysical Journal
سال: 2014
ISSN: 0006-3495
DOI: 10.1016/j.bpj.2013.11.3168